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Bacteriostatic water vs sterile water for reconstitution

The difference between the two most common diluents and when researchers choose each.

In this article
  1. Sterile water
  2. Bacteriostatic water
  3. Compatibility

Both are used to reconstitute lyophilized peptides, but they are not interchangeable in every protocol.

Sterile water

Sterile water contains no additives. It suits single-use preparations, where the entire vial is used at once.

Bacteriostatic water

Bacteriostatic water contains 0.9% benzyl alcohol, which inhibits bacterial growth. That makes it the usual choice when a vial will be accessed several times over a period of days.

Sterile waterBacteriostatic water
PreservativeNone0.9% benzyl alcohol
Typical useSingle useMultiple draws
After openingUse immediatelyRefrigerate, use within protocol limits

Compatibility

A small number of compounds are sensitive to benzyl alcohol or need acidic or buffered diluents. Always check the solubility information for the compound you are working with.

This article is for informational and research purposes only and does not constitute medical advice.

Written by pep1admin More articles

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